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Predictions for 2026: Top Buy & Biggest Short | Why Salesforce Could Win & NVIDIA’s Challenges

Jason Lemkin is one of the leading SaaS investors of the last decade with a portfolio including the likes of Algolia, Talkdesk, Owner, RevenueCat, Saleloft and more. Rory O’Driscoll is a General Partner @ Scale where he has led investments in category leaders such as Bill.com (BILL), Box (BOX), DocuSign (DOCU), and WalkMe (WKME), among others. ----------------------------------------------- Timestamps: 00:00 Intro 01:23 Founder of the Year 2025 08:33 Fund of the Year 21:27 Breakout Companies of 2025: Who Made the Biggest Impact? 28:35 Biggest Surprises of 2025 35:36 Predictions for 2026: Top Performing Tech Stocks of the Year 39:21 B2B Stocks to Watch 41:50 Why Salesforce Could Be the Buy of 2026 54:50 Google, Meta, Apple, NVIDIA, Microsoft: Buy One, Short One 01:01:40 IPO Speculations: Who Will Go Public in 2026 01:07:48 The Impact of AI on Employment ---------------------------------------------------------------------------------------------- Subscribe on Spotify: https://open.spotify.com/show/3j2KMcZ... Subscribe on Apple Podcasts: https://podcasts.apple.com/us/podcast... Follow Harry Stebbings on X: https://x.com/harrystebbings Follow Jason Lemkin on X: https://x.com/jasonlk Follow Rory O’Driscoll on X: https://x.com/rodriscoll Follow 20VC on Instagram: https://www.instagram.com/20vchq Follow 20VC on TikTok: https://www.tiktok.com/@20vc_tok Visit our Website: https://www.20vc.com Subscribe to our Newsletter: https://www.thetwentyminutevc.com/con... ----------------------------------------------- #20vc #harrystebbings #roryodriscoll #jasonlemkin #predictions2026 #buy #short #nvidia #salesforce

Jason LemkinguestRory O’DriscollguestHarry Stebbingshost
Dec 22, 20251h 12mWatch on YouTube ↗

Episode Details

EPISODE INFO

Released
December 22, 2025
Duration
1h 12m
Channel
The Twenty Minute VC
Watch on YouTube
▶ Open ↗

EPISODE DESCRIPTION

Jason Lemkin is one of the leading SaaS investors of the last decade with a portfolio including the likes of Algolia, Talkdesk, Owner, RevenueCat, Saleloft and more. Rory O’Driscoll is a General Partner @ Scale where he has led investments in category leaders such as Bill.com (BILL), Box (BOX), DocuSign (DOCU), and WalkMe (WKME), among others. ----------------------------------------------- Timestamps: 00:00 Intro 01:23 Founder of the Year 2025 08:33 Fund of the Year 21:27 Breakout Companies of 2025: Who Made the Biggest Impact? 28:35 Biggest Surprises of 2025 35:36 Predictions for 2026: Top Performing Tech Stocks of the Year 39:21 B2B Stocks to Watch 41:50 Why Salesforce Could Be the Buy of 2026 54:50 Google, Meta, Apple, NVIDIA, Microsoft: Buy One, Short One 01:01:40 IPO Speculations: Who Will Go Public in 2026 01:07:48 The Impact of AI on Employment ---------------------------------------------------------------------------------------------- Subscribe on Spotify: https://open.spotify.com/show/3j2KMcZ... Subscribe on Apple Podcasts: https://podcasts.apple.com/us/podcast... Follow Harry Stebbings on X: https://x.com/harrystebbings Follow Jason Lemkin on X: https://x.com/jasonlk Follow Rory O’Driscoll on X: https://x.com/rodriscoll Follow 20VC on Instagram: https://www.instagram.com/20vchq Follow 20VC on TikTok: https://www.tiktok.com/@20vc_tok Visit our Website: https://www.20vc.com Subscribe to our Newsletter: https://www.thetwentyminutevc.com/con... ----------------------------------------------- #20vc #harrystebbings #roryodriscoll #jasonlemkin #predictions2026 #buy #short #nvidia #salesforce

SPEAKERS

  • Jason Lemkin

    guest

    SaaS investor and founder of SaaStr, focused on scaling software companies.

  • Rory O’Driscoll

    guest

    Venture capitalist and board member with experience investing in and advising technology companies.

  • Harry Stebbings

    host

    Founder and host of The Twenty Minute VC (20VC), interviewing leading investors and founders.

EPISODE SUMMARY

In this episode of The Twenty Minute VC, featuring Jason Lemkin and Rory O’Driscoll, Predictions for 2026: Top Buy & Biggest Short | Why Salesforce Could Win & NVIDIA’s Challenges explores venture leaders recap 2025, debate AI, and forecast 2026 winners The panel crowns Anthropic (and CEO Dario Amodei) as the defining force behind 2025’s “vibe coding” and agentic-product inflection, while also praising operational leaders like Gwynne Shotwell (SpaceX) and execution-driven founders like Vlad Tenev (Robinhood).

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